Anal Fissure

Original Author: Will Hunt
Last Updated: June 25, 2019
Revisions: 25

An anal fissure is a tear in the mucosal lining of the anal canal, most commonly due to trauma from defecation of hard stool. It can be classified according to its duration:

  • Acute – present for <6 weeks
  • Chronic – present for >6 weeks

Anal fissures can also be categorised by whether they are primary (no underlying disease) or secondary (underlying disease e.g inflammatory bowel disease).


Risk Factors

Anal fissures are usually caused by inflammation or trauma to the anal canal. The major risk factors include:

  • Constipation
  • Dehydration
  • Inflammatory bowel disease
  • Chronic diarrhoea

Clinical Features

The most common presenting feature of an anal fissure is intense pain post-defecation, which can last several hours. Pain can be far out of proportion to the size of the fissure. Other associated symptoms may include bleeding (commonly bright red blood on wiping) or itching, both typically post-defecation.

On examination, fissures can be visible and / or palpable (albeit very painfully) on digital rectal examination. Most fissures present in the posterior midline (90% cases); anterior fissures are more likely to in females or if an underlying cause is present*.

Often patients will refuse a digital rectal examination due to the intense pain and examination under anaesthesia (EUA) may be necessary for diagnosis. Fissures within the anal canal can then usually be identified upon proctoscopy.

The differential diagnoses include haemorrhoids, Crohn’s disease, ulcerative colitis, or anal cancer.

*Multiple fissures or anteriorly located fissures are more likely to be due to an underlying cause and require further investigations (if no known cause is apparent)

Fig 1 - An anal fissure.

Figure 1 – An anal fissure


Management

Medical Management

The medical management of an anal fissure involves reducing risk factors and providing adequate analgesia. The majority of patients do not require surgery.

Measures such as increasing fibre and fluid intake will help. Stool softening laxatives (such as Movicol or Lactulose) can be trialled if there is no change in stool following initial conservative management. Topic anaesthetics, such as lidocaine, or hot baths can help to relax the anal sphincter and also help the healing process.

If patients are still symptomatic, the next line of management is GTN cream or diltiazem cream. This increases the blood supply to the region and relaxes the internal anal sphincter, putting less pressure on the fissure, promoting healing and reducing pain.

Surgical Management

Surgical therapy is reserved for chronic fissures where medical management has failed to resolve the symptoms. Botox injections can be given into the internal anal sphincter, to relax and promote healing. A lateral sphincterotomy can be performed, involving division of the internal anal sphincter muscle.

Recurrence of anal fissures post-surgery is between 1-5%, but studies have shown that the majority of these recurrence patients are those with an underlying predisposition to the condition. The main complication is faecal incontinence.

Key Points

  • Anal fissures present with intense pain post-defecation, as well as potential bleeding or itching
  • Risk factors include constipation and IBD
  • Most cases can be managed conservatively with medical management
  • Consider investigating for underlying causes for those with anterior fissures or recurrent disease

Quiz

Question 1 / 4
What is an anal fissure?

Quiz

Question 2 / 4
What is the most common presenting feature of an anal fissure?

Quiz

Question 3 / 4
Which surgical procedure is most commonly used in the management of an anal fissure?

Quiz

Question 4 / 4
Which laxative is likely to be most suitable for the initial management of an anal fissure?

Results

Medico Digital

Further Reading

Anal Fissure.
Steinhagen E, Diseases of the Colon & Rectum

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